Collagen Type I & III
Type I & III is a supplemental form of collagen. A structural protein family found in connective tissue; supplements often use hydrolyzed "peptides. 20 studies on collagen are available in our database. Learn how collagen type i & iii compares to other forms.
Content reviewed by ZYNAVA Research Team · Last updated February 2026 · Editorial policy
What Is Collagen Type I & III?
Type I & III is a supplemental form of collagen. A structural protein family found in connective tissue; supplements often use hydrolyzed "peptides." Type I/III are common; Type II is used in some joint formulas.
How Collagen Type I & III Compares
Collagen is also available as Hydrolyzed Collagen, Type II, Marine.
About Collagen
A structural protein family found in connective tissue; supplements often use hydrolyzed "peptides."
Find Collagen Type I & III Supplements
Compare collagen type i & iii products and explore your options.
Other Collagen Forms
Compare different forms of collagen and explore your options:
Research on Collagen
Our database contains 20 peer-reviewed studies on collagen:
FAQ: Collagen Type I & III
What is Collagen Type I & III?
Type I & III is a supplemental form of collagen. A structural protein family found in connective tissue; supplements often use hydrolyzed "peptides." Type I/III are common; Type II is used in some joint formulas.
How does Collagen Type I & III compare to other forms?
Collagen is also available as Hydrolyzed Collagen, Type II, Marine.
What other forms of Collagen are available?
Collagen is also available as Hydrolyzed Collagen, Collagen Type II, Collagen Marine, Collagen Bovine. The best form depends on individual absorption, tolerance, and specific needs.
Natural Food Sources of Collagen
Before considering supplementation, it is worth exploring dietary sources of collagen. Whole foods provide nutrients in their natural matrix alongside fiber, enzymes, and other beneficial compounds that can enhance absorption and utilization.
- Bone broth — Simmering bones for 12-24 hours extracts collagen and gelatin into the broth
- Chicken skin — A natural source of type II collagen
- Fish skin — Contains type I collagen, which is similar to human skin collagen
- Pork skin — Used in traditional dishes and as a source of type I and III collagen
- Gelatin — Cooked collagen used in various foods and desserts
Dietary Context
Collagen is the most abundant protein in the body, making up about 30% of total protein. Unlike most nutrients, collagen is not found in plant foods — it is exclusive to animal connective tissues, skin, and bones. The body synthesizes its own collagen using amino acids (particularly glycine, proline, and hydroxyproline) along with vitamin C as a cofactor.
Absorption: Food vs. Supplements
Dietary collagen is broken down into amino acids and peptides during digestion. Hydrolyzed collagen supplements (collagen peptides) are pre-broken-down for easier absorption. Vitamin C is essential for the body's own collagen synthesis, making it an important complementary nutrient.
Practical Tips
- Bone broth is a traditional way to get dietary collagen — longer cooking times extract more
- Vitamin C-rich foods support the body's own collagen production
- Plant foods don't contain collagen but provide the building blocks (amino acids and vitamin C) for collagen synthesis
How to Take Collagen Type I & III
Getting the most from collagen type i & iii supplementation involves more than just choosing the right product. When and how you take it can significantly affect absorption and effectiveness.
Best time to take: On an empty stomach or between meals for best absorption
With or Without Food
Collagen peptides can be taken with or without food, but absorption may be slightly better on an empty stomach. Collagen dissolves easily in both hot and cold liquids.
How Often
Once daily. Most studies showing benefits use 2.5-15 grams daily for 8-12 weeks.
Practical Tips
- Hydrolyzed collagen (collagen peptides) is pre-broken-down for better absorption than gelatin
- Mix into coffee, smoothies, or water — collagen peptides are virtually tasteless
- Pair with vitamin C, which is essential for the body's own collagen synthesis
- Allow 8-12 weeks of consistent use to see skin, joint, or nail benefits
Important Interactions
- Generally very well-tolerated with no known significant drug interactions
- Marine collagen may not be suitable for people with fish allergies
- May cause mild digestive symptoms (bloating, fullness) when starting
This is not an exhaustive list of interactions. Always consult a healthcare provider or pharmacist about potential interactions with your specific medications and health conditions.
Where to Find Collagen Type I & III Supplements
If you are considering collagen type i & iii supplementation, choosing a quality product from a reputable retailer is an important step. Here are some trusted options where you can browse and compare collagen type i & iii supplements.
How to Choose a Quality Collagen Type I & III Supplement
- Look for Good Manufacturing Practice (GMP) certification on the label
- Check whether the product uses the specific form of the ingredient you are looking for
- Review customer feedback and ratings for real-world product experiences
- Consider the supplement form (capsule, powder, liquid, gummy) that best suits your preference
To explore supplements by ingredient or health goal, try our AI Supplement Advisor.
Research Highlights: Collagen Type I & III
Our database includes 2 clinical trials, 2 reviews, 1 meta-analysis examining collagen type i & iii, published between 2024 to 2025. Below are selected findings that illustrate the current state of research. These summaries are educational — not clinical recommendations — and individual outcomes may vary.
Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials
Published in Clin Exp Rheumatol. Study from 2025. Comprehensive analysis combining multiple studies.
Source: View full study on PubMed
Can good sleep quality enhance the benefits of oral collagen supplementation in the prevention of skin aging? A brief report
Published in Arch Dermatol Res. Study from 2025.
Source: View full study on PubMed
Collagen supplementation in metabolic syndrome: a narrative review unraveling the biological mechanisms and effects
Published in Nutr Res Rev. Study from 2025.
Source: View full study on PubMed
Efficacy of combined undenatured type II collagen and hydrolysed collagen supplementation in knee osteoarthritis: a randomised controlled trial
Published in Sci Rep. Study from 2025.
Source: View full study on PubMed
The Effects of Collagen Peptides as a Dietary Supplement on Muscle Damage Recovery and Fatigue Responses: An Integrative Review
Published in Nutrients. Study from 2024.
Source: View full study on PubMed
The research summaries above are based on published peer-reviewed studies and are provided for informational purposes only. Study findings may not apply to all individuals, and the presence of a study summary does not constitute an endorsement of collagen type i & iii for any specific health condition. Always consult a qualified healthcare professional before making decisions based on research findings.
Important Information
Supplements During Pregnancy and Breastfeeding
Pregnancy and breastfeeding create increased demands for specific nutrients, making targeted supplementation particularly relevant during these life stages. Prenatal vitamins typically include higher amounts of folate, iron, and DHA to support fetal development. Folate is especially critical in the early weeks of pregnancy to reduce the risk of neural tube defects, which is why many health organizations recommend women of childbearing age maintain adequate folate intake even before conception.
However, not all supplements are safe during pregnancy. High doses of vitamin A in its retinol form, for example, have been associated with birth defects. Certain herbal supplements lack adequate safety data for use during pregnancy or nursing. ZYNAVA flags pregnancy-related safety considerations where published data is available, but this information is not a substitute for prenatal care. Always work with your obstetrician or midwife to determine which supplements are appropriate for your specific pregnancy.
This Is Not Medical Advice
All content on ZYNAVA, including supplement information pages, research summaries, dosage ranges, and health tool results, is provided for general educational and informational purposes only. Nothing on this website should be interpreted as a diagnosis, treatment recommendation, or substitute for professional medical advice. Supplement research is complex and evolving — study results may not apply to every individual, and what works in a clinical trial may not produce the same results in real-world use.
Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you are pregnant, nursing, taking prescription medications, or managing a chronic health condition. Your doctor or pharmacist can help you evaluate whether a specific supplement is appropriate for your individual circumstances.
This content is for general educational purposes only and is not intended as medical advice. Consult a healthcare professional before starting any supplement. See our full disclaimer and affiliate disclosure.